Sodium etidronate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

影响钙代谢的二磷酸盐。它抑制异位钙化并减缓骨吸收和骨转换。

A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover. (In Vitro):Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.

Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.

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Etidronic Acid | Didronel | HEDP | Hydroxyethylidene Diphosphonic Acid

Proteasome/Ubiquitin

Tyrosinase

protein tyrosine phosphatase

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7414-83-7

249.99

C2H6Na2O7P2

>98% (HPLC)

Water: 11.5 mg/mL

CC(O)(P(O)(O)=O)P(O)(O)=O

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(-20℃)

With Ice Pack

≥ 2 years